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acquired — malignancy, pregnancy, OCP use, inflammatory disease, heparin-induced thrombocytopenia) Once a thrombus forms, it can propagate proximally (distal to proximal extension, increasing PE risk), embolize to the pulmonary arteries (PE — see separate CDG), or undergo fibrinolysis (spontaneous resolution) or organization (becoming chronic/fibrotic)
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Following the peak level, the degree of methaemoglobinemia then decreased faster than that induced by sodium nitrite (Kruszyna et al., 1982)