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As I moved up the line of vehicles, I discovered that there would be a group of 5-10 vehicles with a huge gap between the lead vehicle and the rest of the column

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The rate-limiting step within this pathway is the conversion of tryptophan to its oxidized form N -formylkynurenine (NFK) by one of two enzymes: indoleaninie-2,3-dioxygenase (IDO) or tryptophan-2,3-deoxygenase (TDO)