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Rapid induction of intracellular GSH synthesis occurs in response to various oxidative stress parameters, which is a critical determinant of cellular tolerance to oxidative stress (12)

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This plot assumes that every tooth is treated using a 10 μl “drop” of 38% (w/v) SDF [41], or alternatively 50% (w/v) silver(I) nitrate (SN) and a 20 μL volume of 5% (w/v) sodium fluoride varnish (FV) [42], since these are approximately the volumes that are employed in the field