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TSS pathway activity is suppressed by excess hemin under hypoxia, and the suppression is reversible through DMF treatment The afore findings suggest that supplementing cystine at physiological concentrations is a prerequisite for investigating the function of CBS in SCD erythroblasts

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doi: 10.1128/JCM.31.10.2577-2583.1993 [DOI] [PMC free article] [PubMed] [Google Scholar] McDowell JV, Tran E, Hamilton D, Wolfgang J, Miller K, and Marconi RT (2003)

glutathione consists of three amino acids