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Methods: The current review will include a comprehensive survey of well-established preclinical models, including classic preclinical models including weight drop, blast injury, fluid percussion injury, controlled cortical impact injury, as well as more novel injury models including closed-head impact model of engineered rotational acceleration (CHIMERA) models and closed-head projectile concussive impact model (PCI)
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Additionally, due to limitations of our facilities and environment, we only conducted ERG experiments at flash waves and flicker waves, focusing on the rod-cone response and the effect of DMSO on improving retinal function while we were unable to examine the scotopic response and oscillatory potentials