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Frontiers | Chemical approaches targeting the hurdles of hepatocyte transplantation: mechanisms, applications, and advances
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This is the molecular rationale for the "TB-500" design: synthesizing the 17–23 actin-binding motif as a stand-alone short peptide allows researchers to study an actin-interaction signal independent of the rest of the Tβ4 sequence, in a molecule that is far simpler to synthesize, characterize, and quantify by mass spectrometry
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