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8 It does this by changing a methyl group (a chemical group that changes how molecules act) from S-adenosylmethionine (SAMe) to nicotinamide (NAM), producing 1-methylnicotinamide (MNA).9 Once this happens, MNA is removed from the cell, which simultaneously removes nicotinamide

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The stability problem is one reason why people in the UK are much better off with German hydroxocobalamin