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The insider's guide to leukocyte integrin signalling and function | Nature Reviews Immunology

Cross-sectional studies employing fecal metagenomic sequencing demonstrated significantly reduced α -diversity in the gut microbiota of patients with moderate to severe depressive disorder compared to controls

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In contrast, LDNs display a functionally exhausted phenotype, with reduced chemotactic and immune functions, impairing their ability to eliminate pathogens and necrotic cells [84]

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