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Such a “cobalamin resistance” occurs in geriatric, diabetic, and hemodialysis human patients.53 Alternative explanations could be the shift to an increased pool of circulating cobalamin with hepatic disease53 or a compromised translocation of cobalamin to the intracellular space (which is not reported in dogs)
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It is often discussed for its potential role in supporting healing, especially in tendons, ligaments, muscles, joints, nerves, and other connective tissues
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