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A double-blind, randomized, placebo-controlled crossover study of memantine monotherapy (60 patients, 43 completed) found no significant improvement in Tinnitus Handicap Inventory scores compared with placebo, leading the authors to conclude that the study does not provide evidence to recommend memantine for tinnitus treatment (Figueiredo et al., 2008)
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The Lancet (2023) This Phase 2 trial evaluated CagriSema versus semaglutide alone and cagrilintide alone in 92 adults with type 2 diabetes and overweight or obesity on metformin with or without an SGLT2 inhibitor across 17 US sites
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