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At least 70 enzymes have been identified as requiring CoA or ACP derivatives for their function including the same critical thiamine-dependent enzymes described above, the pyruvate dehydrogenase complex (PDHc), 2-oxoglutarate (α-ketoglutarate) dehydrogenase complex (OGDH), and branched-chain α-ketoacid dehydrogenase complex (BCKD)

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Document both conditions thoroughly