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Astrocytes derived from C9orf72 and sporadic ALS patients were found to be toxic in vitro and in vivo to motor neurons, by a non-cell-autonomous mechanism (Di Giorgio et al., 2007

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We currently have little understanding of the universe of potentially endemic coronaviruses circulating in animal hosts, although a combination of high mutagenic properties and broad host range means that there is a persistent threat of novel zoonotic emergence

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