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(2) lipoxin (LXA)/vehicle group: rats were given vehicle (i.v.) 5 min before LXA administration (7.0 μg/kg per day) into the tail vein (Wu et al., 2013), an ASA-triggered endogenous lipid mediator with potent anti-inflammatory properties agonist of the FPR2/ALX receptor (Medeiros et al., 2013) 5 min before ASA administration (15 mg/kg per day, by oral gavage)