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doi: 10.3389/fonc.2022.1018642 Received 13 August 2022 Accepted 31 October 2022 Published 29 November 2022 Volume 12 - 2022 Edited by Lishun Wang, Fudan University, China Reviewed by Erhu Zhao, Southwest University, China

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When combined, these two peptides stimulate GH release through complementary pathways: CJC-1295 amplifies the GHRH signal while ipamorelin provides an additional stimulus through the ghrelin pathway