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Amino acids as functional nutrients in stress mitigation of aquatic species: mechanisms and applications in aquaculture | Blue Biotechnology | Springer Nature Link

performed a study on the in vivo toxicity of high-dose intravenous nano-hydroxyapatite to Wistar rats and found that the observed health issues in the rats were due to nanoparticle aggregation, which caused drug blockage in pulmonary capillaries (Xie et al., 2010

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Phenotypic plasticity: Driver of cancer initiation, progression, and therapy resistance