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This was principally inspired by the report of BCL6 and CDK12/cyclin K molecular glue degraders, which were retrospectively found to stabilize protein–protein interactions through surficial ligand modifications absent in their nonglue analogs 18,19,20,21,22,80
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Funding Research in the author’s lab has been supported by The University of Texas MD Anderson Cancer Center, National Institutes of Health grants R01CA181196, R01CA244144, and R01CA247992, and Cancer Prevention & Research Institute of Texas grant RP220258 (to BG), and Cancer Center Support (Core) grant P30 CA016672 from the National Cancer Institute, National Institutes of Health (to The University of Texas MD Anderson Cancer Center)
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