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200 A randomized placebo-controlled trial involving 75 subjects with fibromyalgia found 100 mg of oral magnesium (as magnesium chloride) once daily for one month improved scores on the Depression Anxiety Stress Scale and reduced pain severity in a subgroup of participants with mild-to-moderate stress, but had no effect on symptom parameters in those with severe-to-extremely severe stress

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When 1 μM svL4 was included in the topical application with LPS, the epidermis at the end of the 14-day treatment was uniformly of normal thickness, and the dermis was nearly free of neutrophils (Figure 2e and f)