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One study found that hydroxychloroquine, which was prescribed for rheumatoid arthritis and lupus, did not cause hemolysis in 11 African American patients with G6PD deficiency.[ref] With Primaquine, which is dosed on a weekly schedule, there is a need for medical supervision and pre-treatment screening for G6PD.[ref][ref] Quinine has been used for centuries to combat malaria

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Proceedings of the National Academy of Sciences, USA 101, 16976–16981